News

Researchers developed a computational approach to spatially resolve the within read variability or “disorder” in DNA methylation patterns and test if age-associated changes in DNA methylation disorder underlie signals comprising epigenetic clocks.

A joint research team has used stem cells to generate human immune cells for application in cancer immunotherapy. This breakthrough platform is expected to significantly enhance cancer-targeting efficacy.

Researchers described the effects of chemotherapy at the single cell resolution in the bone marrow of Myelodysplastic Syndrome patients. The results help better understand which cellular populations are more sensitive to an epigenetic drug.

Researchers from Queen Mary University of London have found that the molecule RvT4 enhances the body’s natural defences against atherosclerosis (hardening of the arteries) in patients with rheumatoid arthritis.

Researchers from the University of California, Davis showed that abnormal expression of the protein Engrailed-1 (EN1) promotes pancreatic cancer progression and metastasis in vitro and in mouse models.

Researchers recently developed highly realistic simulations of the proteins on sperm and egg cells coupling together before they fuse. These findings enabled the research team to solve several mysteries of fertilisation at once.

The first 3D-printed brain tissue could change the way researchers investigate neurological disorders.

Researchers have captured the world’s first high-resolution images of the initial moments of microtubule formation in human cells.

A precursor of cholesterol can protect cancer cells from a form of cell death known as ferroptosis. The results opens up exciting prospects for further improving the treatment of cancer and other diseases associated with oxidative stress.

Reversible switch permits infection-fighting blood cells to change course to become long-lived memory cells instead of short-lived killer cells.